By Ausin MediHeal · Cardiovascular Health Series
If you've spent any time researching ingredients for heart and circulatory health, chances are you've come across Nattokinase — an enzyme with roots in traditional Japanese cuisine that has become one of the most talked-about additions to cardiovascular-focused supplements worldwide.
But what exactly is it, where does it come from, and how does it fit into a supplement like Clear Blood Vessel (60 Veg Caps)? This guide breaks it down in plain terms.
What Is Nattokinase?
Nattokinase is an enzyme derived from natto, a traditional Japanese food made from soybeans fermented with the bacteria Bacillus subtilis. Natto has been part of the Japanese diet for centuries, and researchers isolated this specific enzyme from the fermentation process due to its unique properties.
Unlike a vitamin or mineral, Nattokinase is a protein-based enzyme, meaning it works differently in the body compared to typical nutrients — which is part of why it's drawn so much research interest over the years.
Why Fermented Soy? A Quick Origin Story
Fermentation transforms the nutritional profile of soybeans, breaking down proteins into different compounds — including the enzyme now sold in supplement form. This is one of the reasons natto is treated differently, nutritionally speaking, from unfermented soy products like tofu or soy milk.
In Singapore, where fermented foods like tempeh and fermented bean curd are already familiar, Nattokinase can feel like a natural extension of foods many households already recognise — just concentrated into a more convenient daily capsule.
How Nattokinase Is Generally Used in Supplements
- Typically standardised and measured in Fibrinolytic Units (FU) for consistency between batches
- Usually taken once daily, often on an empty stomach according to many product labels
- Frequently paired with other vascular-supporting ingredients in combination formulas
- Available primarily in vegetarian capsule form to preserve enzyme stability
What the Research Generally Says
Nattokinase has been studied by researchers interested in its potential role in supporting healthy blood flow and normal circulation. Much of the available research has been conducted in smaller clinical settings, and results can vary based on dosage, formulation, and individual factors.
It's important to note: Nattokinase is a dietary supplement ingredient, not a medication. It has not been evaluated by health authorities to diagnose, treat, cure, or prevent any disease, and it should never be used as a substitute for prescribed treatment for any cardiovascular condition.
Who Should Be Cautious With Nattokinase?
Because of how Nattokinase is believed to interact with the body's natural processes, individuals who are on blood-thinning medication (such as warfarin or aspirin), have a bleeding disorder, are pregnant or breastfeeding, or are scheduled for surgery should speak with a doctor before taking any Nattokinase-containing supplement.
How Clear Blood Vessel Uses Nattokinase
Clear Blood Vessel (60 Veg Caps) includes Nattokinase as part of a broader formula designed to support:
- ✔️ Smooth, healthy blood circulation as part of an active lifestyle
- ✔️ The natural elasticity and suppleness of blood vessel walls
- ✔️ Blood viscosity already within a healthy range
- ✔️ Overall cardiovascular and cerebrovascular wellness
- ✔️ Blood pressure and cholesterol levels already within the normal range
- ✔️ Arterial wall strength as part of general vascular maintenance
- ✔️ Suitable for both men and women
Manufactured in Singapore under GMP-certified standards using vegetarian capsules, Clear Blood Vessel is formulated for daily, long-term use as part of a broader cardiovascular wellness routine — alongside regular movement, a balanced diet, and adequate sleep.
*These statements describe general wellness support and have not been evaluated to diagnose, treat, cure, or prevent any disease. This product does not replace medical treatment for high blood pressure, high cholesterol, or any diagnosed cardiovascular condition. Consult your doctor before use, especially if on blood-thinning medication, pregnant, breastfeeding, or scheduled for surgery.
Frequently Asked Questions
Is Nattokinase the same as natto?
No. Natto is the fermented soybean food itself, while Nattokinase is a specific enzyme extracted and purified from that fermentation process, then standardised for use in supplements.
Can vegetarians take Nattokinase supplements?
Yes. Nattokinase is derived from fermented soybeans, making it plant-based. Clear Blood Vessel also uses vegetarian capsules, so the entire product is suitable for vegetarians.
Can I take Nattokinase with my blood pressure medication?
You should consult your doctor before combining Nattokinase with any prescribed medication, particularly blood-thinning or blood pressure medication, to avoid any potential interaction.
How is Nattokinase different from fish oil or CoQ10 for heart health?
Fish oil and CoQ10 are nutrients that support general cardiovascular wellness through different mechanisms, while Nattokinase is an enzyme studied specifically in relation to blood flow and circulation. Many formulas, including combination cardiovascular supplements, use these ingredients alongside each other rather than as substitutes.