Green Kare
Nourish with Green, Flourish with Care
"Nourish with Green, Flourish with Care" is the foundation on which Green Kare was built.
Green Kare bridges the wisdom of TCM with the efficacy of modern science, creating a series of scientifically crafted formulas with synergistic effects. Each product is designed to help regulate metabolism, address health concerns, and support a balanced, high-performance lifestyle—all without synthetic chemicals or harmful side effects.
Premium HERBAL EXTRACTS are carefully processed using advanced extraction methods and freeze-drying techniques to preserve the full bioavailability and active compounds of each ingredient, ensuring maximum potency and powerful health benefits.
Through clinical insight and advanced formulation techniques, we ensure:
- Optimal ingredient ratios for peak performance.
- Enhanced bioavailability for faster, longer-lasting effects.
- Targeted support for energy, vitality, treatment, and overall health.
With scientific formulations for optimal synergy, potent herbal extracts ingredients, Made in SG, GMP certified facilities, Green Kare represents the highest standard of quality, safety, and efficacy.
Are you ready to flourish and be nourished by Green Kare?
Synergistic Formulation
In Traditional Chinese Medicine (TCM), formula theory (方剂学) explains how multiple herbs are combined to produce synergistic therapeutic effects that are stronger, broader, or safer than single herbs. This is a core feature that distinguishes TCM from single-compound drug therapy.
1. Core Idea of TCM Formula Theory
TCM formulas are designed to:
- Treat complex syndromes (证, Zheng) rather than single diseases
- Address multiple pathological factors at once
- Balance efficacy and efficiency
The therapeutic effect arises from the synergy among herbs, not simple addition.
2. The “Jun–Chen–Zuo–Shi” (君臣佐使) Principle
This is the classical framework for understanding synergy in TCM formulas.
1) Jun (君, Emperor)
- Main therapeutic herb
- Targets the primary disease or syndrome
- Provides the strongest effect
2) Chen (臣, Minister)
- Supports and strengthens the Jun herb
- Treats secondary symptoms or reinforces the main action
3) Zuo (佐, Assistant)
- Enhances the main effect
- Treats accompanying symptoms
- Reduces toxicity or harshness of Jun/Chen herbs
4) Shi (使, Courier/Guide)
- Guides the formula to specific meridians
- Harmonizes the overall formula
3. Types of Synergistic Effects in TCM Formulas
1) Therapeutic Synergy (协同增效)
Multiple herbs act on the same pathological mechanism, increasing efficacy.
2) Functional Complementarity (功能互补)
Different herbs treat different aspects of the syndrome.
- One herb treats the root (本)
- Another treats the branch (标)
3) Pharmacokinetic Synergy (吸收与分布)
Certain herbs:
- Improve absorption
- Enhance bioavailability
- Guide compounds to specific organs (meridian tropism)
4. Modern Interpretation of Synergy
Modern research explains TCM synergy through:
1) Multi-target effects
Different compounds act on:
Inflammation, Immune regulation, Metabolism, and Neuroendocrine systems
2) Chemical interactions
One herb alters solubility or stability of another’s compounds
3) Systems biology view
TCM formulas regulate networks, not single pathways
Advanced Extraction Technology
Supercritical Fluid Extraction (SFE) is a separation technique that uses a fluid above its critical temperature and pressure to selectively dissolve and extract target compounds from solid or liquid matrices. The most commonly used supercritical fluid is carbon dioxide (CO₂)
1. What is a Supercritical Fluid?
A substance becomes supercritical when it is heated and pressurized above its critical point, where it no longer exists as a distinct liquid or gas.
It has gas-like diffusivity and viscosity → penetrates materials easily
It has liquid-like density → good dissolving power
For CO₂:
- Critical temperature: 31.1 °C
- Critical pressure: 7.38 MPa (≈74 bar)
2. Principle of SFE
1)CO₂ is compressed and heated to supercritical conditions.
2)Supercritical CO₂ passes through the sample.
3)Target compounds dissolve in the CO₂.
4)Pressure and/or temperature is reduced in a separator.
5)Extracted compounds precipitate and are collected.
6)CO₂ is recycled or vented.
Key idea: Solubility can be tuned by adjusting pressure and temperature.
3. Advantages of SFE
✅ Low extraction temperature (good for heat-sensitive compounds)
✅ No toxic solvent residues
✅ Environmentally friendly (“green” technology)
✅ High selectivity and purity
✅ CO₂ is non-flammable and recyclable
4. Limitations
❌ High equipment cost
❌ Less effective for very polar compounds without modifiers
❌ Requires high-pressure operation
❌ Process optimization can be complex
5. Comparison with Conventional Extraction
| Feature | SFE | Solvent Extraction |
|---|---|---|
| Temperature | Low | Often high |
| Solvent residue | None | Possible |
| Selectivity | High | Lower |
| Environmental impact | Low | Higher |